[Objective] This study aimed to investigate the elimination regularity of ronidazole residues in chickens. [Method] Normal, healthy, 85-day-old Jinling broilers were selected as experimental chickens and fed with complete feed containing different concentrations of ronidazole. Ronidazole residues in chicken feather and edible tissues were detected by high performance liquid chromatography-tandem mass spectrometry （LC-MS/MS） method to compare the elimination regularity. [Result] Data analysis showed that the amount of ronidazole residues in chicken feather and edible tissues was positively correlated with the concentration of ronidazole administered. After drug withdrawal, there was a significant correlation between the elimination of ronidazole residues in chicken feather and edible tissues. Thus, the prediction model of ronidazole residues in chicken feather could be established. [Conclusion] This study could improve in vivo detection system of ronidazole residues and provide reference for monitoring and controlling drug residues in livestock and poultry oroduction.
[Objective] This study aimed to compare the residue situation of cimaterol,a kind of forbidden veterinary drug in hair, urine and flesh of pig, so as to provide theoretical basis for monitoring veterinary drug residue in bred animals. [Method]Total three different concentrations of cimaterol were administered to pigs, and the residue amounts of cimaterol in pig hair, urine and flesh were monitored at different raising stage. [Result] During the administration period, the residue amount of cimaterol was highest in urine, so urine is the suitable sample for rapid detection of cimaterol in manufacturing enterprises. Cimaterol could be accumulated in pig hair,where cimaterol was metabolized slowly. Thus, pig hair can be used as the test sample for tracing illegal use of veterinary drugs and for vivo detection. Flesh can be used as test sample for direct judgment whether cimaterol residue exceeds the relevant standard. [Conclusion] This study will provide certain theoretical basis for drug monitor in animal husbandry.
